发表文章 | 已在The EMBO Journal、Journal of Neuroinflammation、Age and Ageing和Journal of Nutrition等期刊发表SCI论文70余篇，作为副主编译、编委等参与著作5部，国家发明专利5件。课题组部分论文如下（Google Scholar引用2025/07）： 1. Guo Q, Li ZF, Hu DY, Li PJ, Wu KN, Fan HH, Deng J, Wu HM, Zhang X*, Zhu JH*. The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder. EMBO J., 2025, 44: 2906-2927 2. Wang JY#, Song YD#, Zhang DL#, Cui L#, Guo Q, Fan XF, Hu BL, Deng J, Wu HM, Zhang X*, Zhu JH*. Detection of early Parkinson’s disease using 5-hydroxymethylcytosine episignatures in blood DNA. Age Ageing, 2025, 54: afaf147 3. Wang JY#, Zeng GL#, Tang RT, Luo HT, Song YL, Zhou YY, Huang JF, Zhu SG, Zhang DL, Liu DN, Liu RP, Huang SS, Yuan CX, Zhu JH*, Zhang X*. Data-driven subtypes of Parkinson disease based on dopamine responsiveness. CNS Neurosci. Ther., 2025, 31: e70408. 4. Zhang MD#, Gu MJ#, Wang Q#, Zhang SM, Zhou WX, Liu SB, Liu RP, Huang CP, Zhu JH*, Wu HM*. Tissue zinc restoration alleviates the levodopa-induced dyskinesia via impeding ERK phosphorylation. Eur. J. Nutr., 2025, 64: 159. 5. Fan HH#, Hou NN#, Zhang DL, Liu DN, Tang RT, Luo HT, Song YD, Cui L, Zhang X*, Zhu JH*. Substantia nigra and blood gene signatures and biomarkers for Parkinson’s disease from integrated multicenter microarray-based transcriptomic analyses. Front. Aging Neurosci., 2025, 17:1540830. 6. Zhang F#, Liu YX#, Zhu YY, Yu QY, Msigwa SS, Zeng ZH, Zhang X, Wu HM*, Zhu JH*. Epidemiologic risk and prevention and interventions in Parkinson disease: from a nutrition-based perspective. J. Nutr., 2025, 155: 1019-1030. 7. Ovlyakulov B#, Hu BL#, Kan HY, Guo Q, Li XF, Fan HH, Wu HM, Wang JY, Zhang X*, Zhu JH*. Escitalopram moderately outperforms citalopram towards anti-neuroinflammation and neuroprotection in 6-hydroxydopamine-induced mouse model of Parkinson’s disease. Int. Immunopharmacol., 2024, 139: 112715. 8. Wang JY, Chen JY, Lian YZ, Zhang WY, Wang MY, Liu RP, Chen LH, Zhang X*, Zhu JH*. Reduced platelet 5-HT content is associated with rest tremor in Parkinson’s disease. Parkinsonism Relat. Disord., 2023, 108: 105314. 9. Zhang X#, Wang K#, Ren XL#, Zhang MD, Wu KN, Wu H, Chu ZW, Liu SS, Jiang XX, Zhu JH*, Wu HM*. Zinc deficiency exacerbates behavioral impediments and dopaminergic neuron degeneration in a mouse model of Parkinson disease. J. Nutr., 2023, 153: 167-175. 10. Fan HH#, Zheng J#, Huang XY, Wu KY, Cui L, Dong HJ, Wang Z, Zhang X*, Zhu JH*. An antisense Alu transposon insertion/deletion polymorphism of ALDH1A1 may functionally associate with Parkinson’s disease. BMC Geriatrics, 2022, 22: 427. 11. Fan HH, Li BQ, Wu KY, Yan HD, Gu MJ, Yao XH, Dong HJ, Zhang X*, Zhu JH*. Polymorphisms of cytochromes P450 and glutathione S-transferases synergistically modulate risk for Parkinson’s disease. Front. Aging Neurosci., 2022, 14: 888942. 12. Li ZF#, Cui L#, Jin MM, Hu DY, Hou XG, Liu SS, Zhang X*, Zhu JH*. A Matrigel-based 3D construct of SH-SY5Y cells models the α-synuclein pathologies of Parkinson's disease. Dis. Model Mech., 2022, 15: dmm049125. 13. He JH#, Liu RP#, Peng YM, Guo Q, Zhu LB, Lian YZ, Hu BL, Fan HH, Zhang X*, Zhu JH*. Differential and paradoxical roles of new-generation antidepressants in primary astrocytic inflammation. J. Neuroinflammation, 2021, 18: 47. 14. Zhang HQ#, Wang JY#, Li ZF, Cui L, Huang SS, Zhu LB, Sun Y, Yang R, Fan HH, Zhang X*, Zhu JH*. DNA methyltransferase 1 is dysregulated in Parkinson’s disease via mediation of miR-17. Mol. Neurobiol., 2021, 58: 2620-2633. 15. Cui L#, Hou NN#, Wu HM, Zuo X, Lian YZ, Zhang CN, Wang ZF, Zhang X*, Zhu JH*. Prevalence of Alzheimer’s disease and Parkinson’s disease in China: an updated systematical analysis. Front. Aging Neurosci., 2020, 12: 603854. (PNAS等引用101次) 16. Zhang X#, Zhu LB#, He JH#, Zhang HQ, Ji SY, Zhang CN, Hou NN, Huang CP*, Zhu JH*. Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes. J. Neuroinflammation, 2020, 17: 50. 17. Shao ZQ#, Zhang X#, Fan HH, Wang XS, Wu HM, Zhang L, Cheng WH*, Zhu JH*. Selenoprotein T promotes proliferation and G1-to-S transition in SK-N-SH cells: implications in Parkinson’s disease. J. Nutr., 2019, 149: 2110-2119. 18. Zhang X, Liu RP, Cheng WH*, Zhu JH*. Prioritized brain selenium retention and selenoprotein expression: Nutritional insights into Parkinson’s disease. Mech. Ageing Dev., 2019, 180: 89-96. 19. Zou M#, Li R#, Wang JY, Wang K, Wang YN, Li Y, Ji FX, Sun SN, Huang SS, Fan HH, Huang CP, Zhang X*, Zhu JH*. Association analyses of variants of SIPA1L2, MIR4697, GCH1, VPS13C and DDRGK1 with Parkinson's disease in East Asians. Neurobiol. Aging, 2018, 68: 159.e7-159.e14. 20. Wu HM#, Li T#, Wang ZF, Huang SS, Shao ZQ, Wang K, Zhong HQ, Chen SF, Zhang X*, Zhu JH*. Mitochondrial DNA variants modulate genetic susceptibility to Parkinson’s disease in Han Chinese. Neurobiol. Dis., 2018, 114: 17-23. (Elsevier中国公众号撰文推送) 21. Zhang X, Yang R, Hu BL, Lu P, Zhou LL, He ZY, Wu HM*, Zhu JH*. Reduced circulating levels of miR-433 and miR-133b are potential biomarkers for Parkinson’s disease. Front. Cell. Neurosci., 2017, 11: 170. (被引83次) 22. Fan HH, Zhu LB, Li T, Zhu H, Wang YN, Ren XL, Hu BL, Huang CP, Zhu JH*, Zhang X*. Hyperoside inhibits lipopolysaccharide-induced inflammatory responses in microglial cells via p38 and NFκB pathways. Int. Immunopharmacol., 2017, 50: 14-21. (被引73次) 23. Wang JY#, Zhuang QQ#, Zhu LB, Zhu H, Li T, Li R, Chen SF, Huang CP*, Zhang X*, Zhu JH*. Meta-analysis of brain iron levels of Parkinson’s disease patients determined by postmortem and MRI measurements. Sci. Rep., 2016, 6: 36669. (Nature Neuroscience、Nature Reviews Neurology等引用219次) 24. Lei XG*, Zhu JH, Cheng WH, Bao Y, Ho YS, Reddi AR, Holmgren A, Arner ESJ. Paradoxical roles of antioxidant enzymes: basic mechanisms and health implications. Physiol. Rev., 2016, 96(1): 307-364. (被引463次) 25. Zhang X, Ye YL, Wang YN, Liu FF, Liu XX, Hu BL, Zou M, Zhu JH*. Aldehyde dehydrogenase 2 genetic variations may increase susceptibility to Parkinson's disease in Han Chinese population. Neurobiol. Aging, 2015, 36(9): 2660.e9-2660.e13. 26. Wang JY, Gong MY, Ye YL, Ye JM, Lin GL, Zhuang QQ, Zhang X*, Zhu JH*. The RIT2 and STX1B polymorphisms are associated with Parkinson's disease. Parkinsonism Relat. Disord., 2015, 21(3): 300-302. 27. Zhang X, Cheng X, Hu YB, Lai JM, You H, Hu BL, Zou M, Zhu JH*. Serotonin transporter polymorphic region 5-HTTLPR modulates risk for Parkinson’s disease. Neurobiol. Aging, 2014, 35(8): 1957.e9-1957.e14. 28. Liu RP#, Zou M#, Wang JY, Zhu JJ, Lai JM, Zhou LL, Chen SF, Zhang X*, Zhu JH*. Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling. J. Neuroinflammation, 2014, 11: 47. (被引92次；曾标为期刊 “高访问”论文) 29. Zhao HW#, Lin J#, Wang XB#, Cheng X, Wang JY, Hu BL, Zhang Y*, Zhang X*, Zhu JH*. Assessing plasma levels of selenium, copper, iron and zinc in patients of Parkinson’s disease. PLoS ONE, 2013, 8(12): e83060. (被引121次；曾标为期刊引用排名前25%) |
